BDBM50112179 CHEMBL3608740::US10030025, Compound 20::US10836768, Cpd no 20::US11731974, Compound 20::US9422299, 20::US9987274, Compound 20

SMILES C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccccc1

InChI Key InChIKey=HQFWWFCJWZXHFM-SNVBAGLBSA-N

Data  18 KI  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50112179   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Euroscreen

US Patent
LigandPNGBDBM50112179(CHEMBL3608740 | US10030025, Compound 20 | US108367...)
Affinity DataIC50:  5.00E+4nMAssay Description:The hERG inhibition study aims at quantifying the in vitro effects of compounds of the invention on the potassium-selective IKr current generated in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Euroscreen

US Patent
LigandPNGBDBM50112179(CHEMBL3608740 | US10030025, Compound 20 | US108367...)
Affinity DataIC50:  5.00E+4nMAssay Description:The human ether-a-go-go related gene (hERG) encodes the inward rectifying voltage gated potassium channel in the heart (Igr) which is involved in car...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Euroscreen

US Patent
LigandPNGBDBM50112179(CHEMBL3608740 | US10030025, Compound 20 | US108367...)
Affinity DataIC50:  5.00E+4nMAssay Description:The human ether-a-go-go related gene (hERG) encodes the inward rectifying voltage gated potassium channel in the heart (IKr) which is involved in car...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Euroscreen

US Patent
LigandPNGBDBM50112179(CHEMBL3608740 | US10030025, Compound 20 | US108367...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed